VISION Research Projects – 2nd cohort
A01.2 – Integrative analysis of herpesvirus protein-protein interaction networks
PI: Jens Bosse
@ Centre for Structural Systems Biology (CSSB)
A02.2 – Protein-protein interactions determining influenza A virus assembly and infection cycle in host cells
PI: Jan Kosinski
@ Centre for Structural Systems Biology (CSSB)
A03.2 – Studies into binding of attachment factors and neutralizing antibodies to HEV P-dimers with NMR
PIs: Thomas Peters / Patrick Behrendt
@ Universität zu Lübeck (UzL)
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A04.2 – Modeling interfaces and designing peptides and other molecules to disrupt capsid assembly, stability, and size
PIs: Charlotte Uetrecht / Maya Topf
@ Centre for Structural Systems Biology (CSSB)
B01.2 – Structural investigation of the herpesvirus entry complex
Kay Grünewald
@ Centre for Structural Systems Biology (CSSB)
B02.2 – Characterization of SR-B1-mediated lipid transfer
PIs: Thomas Krey/ Gabrielle Vieyres
@ Universität zu Lübeck (UzL)
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C01.2 – Structural and functional investigation of herpesviral latent and immediate early lytic proteins
PIs: Lars Redecke/ Thomas Schulz/ Melanie Brinkmann
@ Universität zu Lübeck (UzL)
C02.2 – Structural analysis of MCPyV encoded LT Antigen/DNA binding
Nicole Fischer / Arwen Pearson
@ University Medical Center Hamburg-Eppendorf (UKE)
C03.2 – Structural and functional analysis of pestiviral NS2pro-NS3pro precursors
PIs: Norbert Tautz / Arwen Pearson
@ Universität zu Lübeck (UzL)
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C04.2 – The role of the non-classical deSUMOylase LUNA from HCMV in viral reactivation from latency
PIs: Janna Bigalke / Thomas Krey
@ Universität zu Lübeck (UzL)
C05.2 – Virtual screening for compounds binding to LASV proteins and functional validation
PIs: Maria Rosenthal / Maya Topf
@ Centre for Structural Systems Biology (CSSB)